I need it to be compatible with USB 2.0 and MIDI. I need the necessary number of inputs/outputs for the following gear:

1) Guitar-->Amp-->Mic-->Interface-->PC
2) MIDI Synth-->Amp-->Mic-->Interface-->PC
3) MIDI Synth-->Interface-->PC
4) Vocals-->Interface-->PC

I have a three mics; one condenser and two dynamic (instrument and vocal). For recording I'm thinking of using 2 mics at a time. I'm looking for something relatively small, but am torn because I might need to record drums one day as well.

A recording software suggestion would be excellent as well. I'm new to recording and want some bang-for-my-buck. My price range is up to $250, used or new, cheaper is better. Thank You!